Searchable abstracts of presentations at key conferences in endocrinology

ea0016p34 | Adrenal | ECE2008

Renal excretion rates of free cortisol, free cortisone and dehydroepiandrosterone metabolites, but not renal indices of cortisol secretion are associated with urinary volume in healthy children

Shi Lije , Wudy Stefan A , Maser-Gluth Christiane , Hartmann Michaela F , Remer Thomas

Background: In experimental studies, a high fluid intake and a corresponding high urine volume have been shown to increase renal excretion rates of urinary free cortisol (UFF) and cortisone (UFE) in adults. We aimed to examine whether 24-h urinary steroid excretion rates are also affected by urine volume in children.Methods: In 24-h urine samples of 100 prepubertal and 100 pubertal healthy children UFF, UFE, tetrahydrocortisol, 5α-tetrahydrocortisol...